About the vaccines
For
U.S. Residents Only
For
U.S. Residents Only

SUPERIOR FLU PROTECTION FOR ADULTS 65+

COMPARED TO STANDARD-DOSE FLUZONE VACCINE

Your immune system ages right along with you, which can make it harder to fight off infections like the flu.1
FLUZONE® HIGH-DOSE INFLUENZA VACCINE is specifically formulated for people 65+.2,3 It’s proven to be 24.2% more effective than Fluzone vaccine in preventing the flu.3

FLUZONE® HIGH-DOSE vaccine is indicated for people 65 years of age and older to help prevent influenza disease caused by influenza A and B strains contained in the vaccine.3

Injection-site reactions and systemic side effects were more frequent after vaccination with FLUZONE® HIGH-DOSE compared to standard-dose Fluzone vaccine.3

the standard dose3,4

THE FLU CAN BE SCARY FOR PEOPLE 65+

Older adults may have a greater risk of complications from the flu.

The CDC estimates that each year, approximately

90% of flu-related deaths

50%-70% of flu-related hospitalizations

in the U.S. occur in people 65 years of age and older.2,9

That’s why it’s important for seniors to get superior flu protection compared to Fluzone influenza vaccine.3,10 Ask your health care professional if FLUZONE® HIGH-DOSE vaccine is an option for you.

IT’S NEVER
TOO LATE TO
GET A FLU SHOT

FIND ONE NEAR YOU

COVERAGE UNDER MAJOR HEALTH PLANS

FLUZONE® HIGH-DOSE vaccine is free with Medicare Part B, and it may be covered with no co-payment or deductible under Medicare Advantage and private insurance plans.

FLUZONE® QUADRIVALENT INFLUENZA VACCINE

Helps protect people as young as 6 months of age against 4 different strains of the flu contained in the vaccine.4

FLUBLOK® QUADRIVALENT INFLUENZA VACCINE

Proven flu protection in adults 50+, compared to a standard-dose vaccine.5

What are Flublok Quadrivalent, Fluzone Quadrivalent, and Fluzone High-Dose vaccines?

Flublok Quadrivalent, Fluzone Quadrivalent, and Fluzone High-Dose vaccines are given to help prevent influenza disease caused by influenza A and B strains contained in each vaccine. Flublok Quadrivalent vaccine is given to people 18 years of age and older. Fluzone Quadrivalent vaccine is given to people 6 months of age and older. Fluzone High-Dose vaccine is given to people 65 years of age and older.

Important Safety Information for Flublok Quadrivalent, Fluzone Quadrivalent, and Fluzone High-Dose Vaccines

Flublok Quadrivalent, Fluzone Quadrivalent, and Fluzone High-Dose vaccines should not be given to anyone who has had a severe allergic reaction (eg, anaphylaxis) to any component of the vaccine (including egg or egg products for Fluzone Quadrivalent and Fluzone High-Dose vaccines) or after a previous dose of the corresponding vaccine. In addition, Fluzone Quadrivalent and Fluzone High-Dose vaccines should not be given to anyone who has had a severe allergic reaction after a previous dose of any influenza vaccine.

Tell your health care professional if you/your child have ever experienced Guillain-Barré syndrome (severe muscle weakness) after a previous dose of influenza vaccine. If you notice any other problems or symptoms following vaccination, please contact your health care professional immediately.

In adults, the most common side effects to Flublok Quadrivalent, Fluzone Quadrivalent, and Fluzone High-Dose vaccines include pain where the shot was given; headache and muscle aches. In children, the most common side effects to Fluzone Quadrivalent vaccine include pain, redness, and swelling where the shot was given; muscle aches, fatigue, and headache (irritability, abnormal crying, drowsiness, appetite loss, vomiting, and fever in young children). Other adverse reactions to these vaccines may occur. Vaccination with Flublok Quadrivalent, Fluzone Quadrivalent, or Fluzone High-Dose vaccine may not protect all individuals.

For more information, talk to your health care professional and refer to the full Prescribing Information for Flublok Quadrivalent, Fluzone Quadrivalent, or Fluzone High-Dose. Also, please see Patient Information for Fluzone Quadrivalent or Fluzone High-Dose vaccine.

References

  1. Aspinall R, Del Giudice G, Effros RB, Grubeck-Loebenstein B, Sambhara S. Challenges for vaccination in the elderly. Immun Ageing. 2007;4:9.
  2. Hamborsky J, Kroger A, Wolfe C. Influenza. In: Hamborsky J, Kroger A, Wolfe C, eds. Epidemiology and Prevention of Vaccine-Preventable Diseases (The Pink Book). 13th ed. Washington, DC: Public Health Foundation; 2015:187-208.
  3. Fluzone High-Dose vaccine [Prescribing Information]. Swiftwater, PA: Sanofi Pasteur Inc.
  4. Fluzone Quadrivalent vaccine [Prescribing Information]. Swiftwater, PA: Sanofi Pasteur Inc.
  5. Flublok Quadrivalent vaccine [Prescribing Information]. Meriden, CT: Protein Sciences Corporation.
  6. Centers for Disease Control and Prevention (CDC). Are you at high risk for serious illness from flu? https://www.cdc.gov/features/fluhighrisk/index.html. Accessed August 1, 2019.
  7. Centers for Disease Control and Prevention (CDC). How the flu virus can change: “shift” and “drift.” https://www.cdc.gov/flu/about/viruses/change.htm. Accessed August 1, 2019.
  8. Centers for Disease Control and Prevention (CDC). Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices—United States, 2018–19 influenza season. MMWR Recomm Rep. 2018;67(3):1-20.
  9. Centers for Disease Control and Prevention (CDC). People 65 years and older & influenza. https://www.cdc.gov/flu/highrisk/65over.htm. Accessed August 1, 2019.
  10. Wang CS, Wang ST, Lai CT, Lin LJ, Chou P. Impact of influenza vaccination on major cause-specific mortality. Vaccine. 2007;25(7):1196-1203.
  11. Centers for Disease Control and Prevention (CDC). Recommended child and adolescent immunization schedule for ages 18 years or younger. https://www.cdc.gov/vaccines/schedules/downloads/child/0-18yrs-child-combined-schedule.pdf. Accessed August 1, 2019.
  12. Centers for Disease Control and Prevention (CDC). Children & influenza (flu). https://www.cdc.gov/flu/highrisk/children.htm. Accessed August, 2019.
  13. IQVIA™. Remittance Data for Fluzone HD August 2018-March 2019 (claim derived from the use of information under license from IQVIA, which expressly reserves all rights, including rights of copying, distribution, and republication).
  14. Flu shots. Medicare Interactive. https://www.medicareinteractive.org/get-answers/medicare-covered-services/preventive-services/flu-shots. Accessed August 7, 2019.
  15. Medicare Part B Immunization Billing: Seasonal Influenza Virus, Pneumococcal, and Hepatitis B. Medical Learning Network website. https://www.cms.gov/Outreach-and-Education/Medicare-Learning-Network-MLN/MLNProducts/Downloads/qr_immun_bill.pdf. Accessed August 7, 2019.
  16. Flu shots. Medicare.gov. https://www.medicare.gov/coverage/flu-shots. Accessed August 7, 2019.
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SAUS.SFLU.19.08.4258a Last Updated: 10/19