The most common local and systemic adverse reactions to Fluzone and Fluzone High-Dose vaccines include soreness, pain, and swelling at the vaccination site; fever, headache, malaise, and myalgia. Erythema, induration, swelling, and pruritus at the vaccination site occur more frequently with Fluzone Intradermal vaccine than with Fluzone vaccine. Other adverse reactions to Fluzone Intradermal vaccine include pain, headache, myalgia, and malaise. Adverse reactions other than those listed above may occur.

Fluzone, Fluzone Intradermal, and Fluzone High-Dose vaccines should not be administered to anyone with a severe allergic reaction (eg, anaphylaxis) to any vaccine component, including egg protein, egg products, or thimerosal (the multi-dose vial of Fluzone vaccine is the only presentation that contains thimerosal), or to a previous dose of any influenza vaccine. The decision to give Fluzone, Fluzone Intradermal, or Fluzone High-Dose vaccine should be based on the potential benefits and risks, especially if Guillain-Barré syndrome has occurred within 6 weeks of receipt of a prior influenza vaccine. Vaccination with Fluzone, Fluzone Intradermal, or Fluzone High-Dose vaccines may not protect all individuals.

Before administering Fluzone vaccine, please see full Prescribing Information.
Before administering Fluzone Intradermal vaccine, please see full Prescribing Information.
Before administering Fluzone High-Dose vaccine, please see full Prescribing Information.