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Sanofi Pasteur: The vaccines division of Sanofi-Aventis group
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Intradermal or Fluzone High-Dose vaccine

Important Safety Information


Fluzone, Fluzone Intradermal, and Fluzone High-Dose vaccines are given to help prevent influenza disease caused by influenza A and B strains contained in each vaccine.

Fluzone vaccine is intended for persons 6 months of age and older. Fluzone Intradermal vaccine is intended for persons 18 through 64 years of age. Fluzone High-Dose vaccine is intended for persons 65 years of age and older.

Approval of Fluzone High-Dose vaccine is based on superior immune response relative to Fluzone vaccine. Data demonstrating a decrease in influenza disease after vaccination with Fluzone High-Dose vaccine relative to Fluzone vaccine are not available.

Safety Information

Side effects to Fluzone and Fluzone High-Dose vaccines include pain, redness, and swelling at the injection site; muscle aches, fatigue, headache, and fever (irritability, abnormal crying, drowsiness, appetite loss, and vomiting in young children receiving Fluzone vaccine). Redness, firmness, swelling, and itching at the injection site occur more frequently with Fluzone Intradermal vaccine than with Fluzone vaccine. Other side effects to Fluzone Intradermal vaccine include pain at the injection site. Other side effects may occur. Fluzone, Fluzone Intradermal, and Fluzone High-Dose vaccines should not be administered to anyone with a severe allergic reaction (eg, anaphylaxis) to any vaccine component, including eggs, egg products, or thimerosal (the multidose vial is the only presentation containing thimerosal), or to a previous dose of any influenza vaccine.

Tell the doctor if you/your child has ever experienced Guillain-Barré syndrome (severe muscle weakness) after a previous dose of influenza vaccine. If you notice any other problems or symptoms following vaccination, please contact your health care professional immediately. Vaccination with Fluzone, Fluzone Intradermal, or Fluzone High-Dose vaccine may not protect all individuals.

For more information about Fluzone, Fluzone Intradermal, and Fluzone High-Dose vaccines, talk to your health care professional and see complete Patient Information.


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