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we've got a flu vaccine specially formulated for you.1

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Ask your health care provider about Fluzone
Intradermal or Fluzone High-Dose vaccine

We've got a flu vaccine specially formulated for you.1

We've got a flu vaccine specially formulated for you.

At 65+, you're not slowing down, but your immune system might be.2,3

You may not know it, but as you get older, your immune system weakens.2,3 Fluzone High-Dose vaccine is the first and only influenza vaccine specially formulated for people 65 years of age and older.4,5 It has 4 times the antigen of a regular flu shot for a stronger immune response to the flu.4,6 This helps your body make antibodies, substances that can help detect and fight off viruses like influenza.1,6 As a result, when compared to traditional influenza vaccines, Fluzone High-Dose vaccine can provide a stronger immune response in older adults.1,6

There are different types of flu.6,7 Fluzone High-Dose vaccine helps protect against the flu virus strains (subtypes A and type B) contained in the vaccine, and not everyone will get the same level of protection.1

Image: 4x the antigen of a regular flu shot

Consider these facts:

  • In the coming years, the population of those 65+ in the United States will increase by at least 9000 every day8

  • Up to 90% of flu-related deaths occur in the elderly, despite high vaccination rates historically9,10

  • One study found that for every influenza-related death in those 65+, there were 4 hospitalizations11

Why Fluzone High-Dose vaccine may be right for you

Studies have shown that Fluzone High-Dose vaccine is safe for people ages 65 years and older.1 Fluzone High-Dose vaccine is given by injection (shot) in the arm.1 You may have soreness, pain, swelling, and redness at the injection site; fever, headache, fatigue, and muscular pain.1 Fluzone High-Dose vaccine is not appropriate for everybody. Do not receive Fluzone High-Dose vaccine if you or your loved one:1

  • Is under 65 years of age1

  • Has ever had an allergic reaction to a flu vaccine1

  • Is allergic to eggs or egg products1

If you or a loved one is moderately or severely ill at the time of your vaccination, talk to a health care provider about whether or not to reschedule.6 Your doctor may recommend waiting until the illness has gone away.6 Typically, people with a mild illness can still get the vaccine.6

Fluzone High-Dose vaccine FAQ

Here are some answers to frequently asked questions about Fluzone High-Dose vaccine.

CDC Influenza Alert

For people age 65 and older, flu-related hospitalization rates are the highest they have been in the past seven years.14

There’s a Fluzone vaccine for you.

Fluzone High-Dose vaccine is the first and only influenza vaccine designed specifically for people 65 years of age and older.4,5

Important Safety Information

Indication

Fluzone, Fluzone Intradermal, and Fluzone High-Dose vaccines are given to help prevent influenza disease caused by influenza A and B strains contained in each vaccine.

Fluzone vaccine is intended for persons 6 months of age and older. Fluzone Intradermal vaccine is intended for persons 18 through 64 years of age. Fluzone High-Dose vaccine is intended for persons 65 years of age and older.

Approval of Fluzone High-Dose vaccine is based on superior immune response relative to Fluzone vaccine. Data demonstrating a decrease in influenza disease after vaccination with Fluzone High-Dose vaccine relative to Fluzone vaccine are not available.

Safety Information

Side effects to Fluzone and Fluzone High-Dose vaccines include pain, redness, and swelling at the injection site; muscle aches, fatigue, headache, and fever (irritability, abnormal crying, drowsiness, appetite loss, and vomiting in young children receiving Fluzone vaccine). Redness, firmness, swelling, and itching at the injection site occur more frequently with Fluzone Intradermal vaccine than with Fluzone vaccine. Other side effects to Fluzone Intradermal vaccine include pain at the injection site. Other side effects may occur. Fluzone, Fluzone Intradermal, and Fluzone High-Dose vaccines should not be administered to anyone with a severe allergic reaction (eg, anaphylaxis) to any vaccine component, including eggs, egg products, or thimerosal (the multidose vial is the only presentation containing thimerosal), or to a previous dose of any influenza vaccine.

Tell the doctor if you/your child has ever experienced Guillain-Barré syndrome (severe muscle weakness) after a previous dose of influenza vaccine. If you notice any other problems or symptoms following vaccination, please contact your health care professional immediately. Vaccination with Fluzone, Fluzone Intradermal, or Fluzone High-Dose vaccine may not protect all individuals.

For more information about Fluzone, Fluzone Intradermal, and Fluzone High-Dose vaccines, talk to your health care professional and see complete Patient Information.

References

  1. Fluzone High-Dose vaccine [Prescribing Information]. Swiftwater, PA: Sanofi Pasteur Inc.; 2014.
  2. Aspinall R, Del Giudice G, Effros RB, Grubeck-Loebenstein B, Sambhara S. Challenges for vaccination in the elderly. Immun Ageing. 2007;4:9.
  3. Monto AS, Ansaldi F, Aspinall R, et al. Influenza control in the 21st century: optimizing protection for older adults. Vaccine. 2009;27(37):5043-5053.
  4. Centers for Disease Control and Prevention (CDC). Licensure of a high-dose inactivated influenza vaccine for persons aged ≥65 years (Fluzone High-Dose) and guidance for use—United States, 2010. MMWR. 2010;59(16):485-486.
  5. CDC. Advisory Committee on Immunization Practices (ACIP) recommended immunization schedule for adults aged 19 years or older - United States, 2014. MMWR. 2014a;63(5):110-112.
  6. Atkinson W, Wolfe S, Hamborsky J, McIntyre L, eds. Epidemiology and Prevention of Vaccine-Preventable Diseases (The Pink Book). 12th ed. Washington, DC: Public Health Foundation; 2011.
  7. Treanor JJ. Influenza viruses, including avian influenza and swine influenza. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, PA: Churchill Livingstone Elsevier; 2010:2265-2288.
  8. United States Government Accountability Office (GAO). The Federal Government's Long-Term Fiscal Outlook, Fall 2012. Washington, DC: United States Government Accountability Office; 2013. GAO-13-148SP.
  9. CDC. Estimates of deaths associated with seasonal influenza—United States, 1976-2007. MMWR. 2010;59(33):1057-1062.
  10. Setse RW, Euler GL, Gonzalez-Feliciano AG, et al. Influenza vaccination coverage—United States, 2000-2010. MMWR. 2011;60(01):38-41.
  11. Molinari NA, Ortega-Sanchez IR, Messonnier ML, et al. The annual impact of seasonal influenza in the US: measuring disease burden and costs. Vaccine. 2007;25(27):5086-5096.
  12. Thompson WW, Shay DK, Weintraub E, et al. Influenza-associated hospitalizations in the United States. JAMA. 2004;292(11):1333-1340.
  13. Center for Medicare and Medicaid Services (CMMS). 2012-2013 Immunizers' Question and Answer Guide to Medicare Part B, Medicaid and CHIP Coverage of Seasonal Influenza and Pneumococcal Vaccinations. Baltimore, MD: Center for Medicare and Medicaid Services; 2012.
  14. CDC. Laboratory confirmed influenza hospitalizations, 2006-2007 to 2012-2013. http://gis.cdc.gov/grasp/fluview/FluHospChars.html. Accessed September 19, 2014.

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